Author

Ko-Chen Chen

National Taiwan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Ruby Yun‐Ju HuangiD· 2 shared Wei‐Chou LiniD· 2 shared Bor‐Ching SheuiD· 1 shared Chin‐Jui WuiD· 1 shared Chun‐Yao HuangiD· 1 shared Denis Ting-Hsian Chen· 1 shared Duncan Yi-Te WangiD· 1 shared Feng‐Chiao TsaiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ruby Yun‐Ju HuangORCID

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2 papers

Recent·Most cited

Spatial transcriptomic profiling of ovarian clear cell carcinoma reveals heterogeneity in OXPHOS and EMT gradients

Thang Truong Le, Duncan Yi-Te Wang, Simin Yan, Yi-Cian Chen, Ko-Chen Chen, Tuan Zea Tan, Pei-Yu Chu, Denis Ting-Hsian Chen, Yi-Chia Chiu, Jia-Yuh Sheu, Sydney Rechie S. Necesario, Chun‐Yao Huang, Jieru Ye, Ya-Ting Tai, Hsueh‐Fen Juan, , Ruby Yun‐Ju Huang

This study uses spatial transcriptomics to reveal OXPHOS and EMT gradients in ovarian clear cell carcinoma, linking metabolic shifts and LCN2 expression to tumor heterogeneity and outcomes.

Nature Communications · Jul 8, 2026Peer-reviewedCancer Biology

Inter- and intra-tumor heterogeneous immune presentation in primary uterine carcinosarcoma determined by digital spatial profiling

Ying-Xuan Li, Wei‐Chou Lin, Ko-Chen Chen, Wen‐Chun Chang, Chin‐Jui Wu, Lin‐Hung Wei, Ruby Yun‐Ju Huang, Bor‐Ching Sheu

This study uses spatial profiling to identify immune subtype differences in UCS tumors, linking immune features to patient survival outcomes.

bioRxiv · Sep 5, 2024 · PreprintImmunology