Author

Kristina Hellberg

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Florentina NegoitaiD· 2 shared Kei SakamotoiD· 2 shared Conchita Fraguas BringasiD· 1 shared Dawn ThompsoniD· 1 shared Gajanan J. SatheiD· 1 shared Gopal P. SapkotaiD· 1 shared Hongling LiuiD· 1 shared James N. HislopiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Florentina NegoitaORCID

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2 papers

Recent·Most cited

Substrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors

Samuel J. Atkinson, Florentina Negoita, Yuichiro Ioi, William V. Ritchie, Kyle Thompson, Max Gardner, Peter T. Ashdown, Kristina Hellberg, Terunao Takahara, Kei Sakamoto, Dawn Thompson, James N. Hislop, Riko Hatakeyama

This study shows that GPCRs regulate mTORC1 substrates differently, with M5R promoting protein synthesis while allowing lysosome biogenesis.

Biochemical Journal · Aug 20, 2026Peer-reviewedCell Biology

AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation

Florentina Negoita, Conchita Fraguas Bringas, Kristina Hellberg, Katarzyna Müller Luda, Hongling Liu, Joyceline Cuenco, Jin‐Feng Zhao, Gajanan J. Sathe, Gopal P. Sapkota, Kei Sakamoto

The paper shows that AMPK activation leads to dephosphorylation of TFEB's C-terminal sites, promoting its transcriptional activation, and that AMPK is not required for mTORC1-mediated TFEB activation.

bioRxiv · Oct 22, 2024 · PreprintBiochemistry