Regulation of NFKBIZ by precise Regnase-1 endoribonuclease cleavage and subsequent uridylation
Samira Ebrahimi, Richard Zapf, Isabelle Gracien, Krysta Koyle, Ryan D. Morin, Timothy E. Audas, Peter J. Unrau
The paper shows Regnase-1 cleaves and uridylates NFKBIZ mRNA, enhancing its decay and linking this process to lymphoma and viral pathogenesis.
bioRxiv · Sep 19, 2025 · PreprintBiochemistry