The role of medicinal Cu2+ salts in expanding the multi-pathway application of tigecycline against drug-resistant bacteria
Jinjing Xue, Qianyu Zhou, Yuanyuan Liu, Lin Ma, Houru Liu, Qianghua Lv, Kuan Gu, Jianfeng Wang, Yonglin Zhou
This study identifies Cu2+ salts as adjuvants that restore tigecycline's antibacterial activity under light exposure by modulating its photolysis pathway.
bioRxiv · Oct 9, 2025 · PreprintBiochemistry