DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer
Benjamin B. Morris, Simon Heeke, Yuanxin Xi, Lixia Diao, Qi Wang, Pedro Rocha, Edurne Arriola, Myung Chang Lee, Darren R. Tyson, Kyle Concannon, Kavya Ramkumar, Catherine Allison Stewart, Robert J. Cardnell, Runsheng Wang, Vito Quaranta, , Lauren A. Byers
This study identifies three distinct DDR phenotypes in SCLC associated with chemotherapy response and tumor evolution.
Molecular Cancer · Mar 20, 2025Peer-reviewedCancer Biology