BCL-XL Dependence is a Subtype Agnostic Actionable Feature of Difficult-to-Treat Kidney Cancers
Tupa Basuroy, Treg M. Grubb, Ananthan Sadagopan, Xingping Qin, Kylee Madison, Autumn Hall, Belinda B. Willard, Sakari Vanharanta, Kristopher A. Sarosiek, Srinivas R. Viswanathan, Abhishek A. Chakraborty
The paper identifies BCL-XL dependence as a common vulnerability in various kidney cancer subtypes and develops a model to predict it using biomarkers like AMPK activation.
Cell Death and Disease · Sep 11, 2026Peer-reviewedCancer Biology