Drug Interactions Between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine
S. Walimbwa, M. Lamorde, C. Waitt, J. Kaboggoza, L. Else, P. Byakika-Kibwika, A. Amara, J. Gini, M. Winterberg, J. Chiong, J. Tarning, S. H. Khoo
This study investigates drug interactions between dolutegravir and artemether-lumefantrine or artesunate-amodiaquine, finding no significant changes in most drug concentrations but a decrease in dolutegravir trough levels with both combinations.
bioRxiv · Jun 20, 2018Pharmacology & Toxicology