An expanded proteomic survey of the human parasite Leishmania major focusing on changes in null mutants of the Golgi GDP-Mannose/Fucose/Arabinopyranose transporter LPG2 or the mitochondrial fucosyltransferase FUT1
G. Polanco, N. E. Scott, L. F. Lye, S. M. Beverley
This paper uses ultradeep proteomics to analyze Leishmania major mutants, revealing significant proteomic changes in LPG2 and FUT1 mutants and highlighting potential therapeutic targets.
bioRxiv · Oct 29, 2022 · PreprintMicrobiology