A comprehensive transcriptional signature in pancreatic ductal adenocarcinoma reveals new insights into the immune and desmoplastic microenvironment
I. Perez-Diez, Z. Andreu, M. R. Hidalgo, C. Perpina-Clerigues, L. Fantin, A. Fernandez-Serra, M. de la Iglesia-Vaya, J. A. Lopez-Guerrero, F. Garcia-Garcia
This study identifies 1153 dysregulated genes in PDAC that shape the desmoplastic stroma and immunosuppressive microenvironment, revealing two gene signatures and five novel prognostic immune genes.
bioRxiv · Mar 31, 2023 · PreprintCancer Biology