Author

L. J. Rogers

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Immunology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Azevedo-Pouly· 1 shared B. Koss· 1 shared L. Burdine· 1 shared L. C. Morehead· 1 shared L. E. Appell· 1 shared M. Barker· 1 shared M. S. Burdine· 1 shared Z. J. Waldrip· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. C. Azevedo-Pouly

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJun 23, 2022

Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

A. C. Azevedo-Pouly, L. E. Appell, L. Burdine…·M. S. Burdine

This study shows DNA-PKcs inhibition reduces T cell activation, cytotoxicity, and metabolic activity in both murine and human models, suggesting its therapeutic potential for immune-related diseases.

DOI 10.1101/2022.06.23.497236

mousehuman