Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis reduces risk of subsequent viral challenge
L. M. Frenkel, L. Kuller, I. A. Beck, C.-C. Tsai, J. P. Joy, T. M. Mulvania, D. C. Montefiori, D. M. Anderson
The paper shows that repeated exposure to live SIVmne or HIV-2287 during antiretroviral prophylaxis in macaques induced non-neutralizing antibodies and partial protection against subsequent viral challenge.
bioRxiv · Sep 30, 2020Immunology