Interaction of Amphiphilic Lipoarabinomannan with Host Carrier Lipoproteins in Tuberculosis Patients: Implications for Blood-based Diagnostics.
H. Mukundan, S. Jakhar, R. Sakamuri, D. Vu, P. Dighe, L. R. Stromberg, L. Lilley, N. Hengartner, B. I. Swanson, E. Moreau, S. E. Dorman
This study evaluates two serum assays for detecting LAM in tuberculosis patients, finding that the membrane insertion assay outperforms the lipoprotein capture assay in specificity and sensitivity.
bioRxiv · Nov 20, 2020Microbiology