Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis
R. S. Jansen, L. Mandyoli, R. Hughes, S. Wakabayashi, J. Pinkham, B. Selbach, K. Guinn, E. J. Rubin, J. C. Sacchettini, K. Rhee
This study identifies Rv3722c as the primary aspartate aminotransferase in Mtb, revealing its role in nitrogen distribution and highlighting it as a potential drug target.
bioRxiv · Sep 26, 2019Microbiology