L. Marrec

Challenges and pitfalls of inferring microbial growth rates from lab cultures

This study identifies challenges in estimating microbial growth rates from lab cultures and shows that inaccurate estimates affect relative fitness calculations.

Quantifying the impact of genotype-dependent gene flow on mutation fixation in subdivided populations

This study quantifies how genotype-dependent gene flow affects mutation fixation in subdivided populations, finding similar fixation probabilities but different fixation times between island and stepping stone models.

Solving the stochastic dynamics of population growth

The paper compares deterministic and stochastic models of population growth, showing deterministic models overestimate population sizes and introduces two novel solutions for stochastic dynamics.

Evolutionary rescue in a fluctuating environment

This study models evolutionary rescue in fluctuating environments, finding that stochastic fluctuations and shorter environmental cycles increase rescue likelihood, while larger populations and higher growth rates improve survival chances.

Toward a universal model for spatially structured populations

The paper introduces a universal model for spatially structured populations that shows how migration asymmetry can shift fixation probabilities of mutants between amplifying and suppressing natural selection.

Adapt or perish: Evolutionary rescue in a gradually deteriorating environment

This study examines evolutionary rescue in a deteriorating environment, showing that later appearing mutants have higher fixation probability and rescue likelihood increases with carrying capacity and mutation probability.

Resist or perish: fate of a microbial population subjected to a periodic presence of antimicrobial

This paper models how periodic antimicrobial exposure affects microbial resistance evolution and population survival, finding that fast alternations favor resistance while longer periods can lead to extinction.

Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance

This study develops a multiscale model showing that antibody-mediated bacterial clustering in the gut can hinder the spread of antibiotic resistance in host populations.

Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in a homogeneous microbial population of fixed size

This study quantifies how periodic antimicrobial presence accelerates resistance evolution in microbial populations, showing faster resistance emergence with shorter periods and larger population sizes.