Author

L. Pesonen

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Cell Biology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. de Thonel· 1 shared D. Saberan-Djoneidi· 1 shared P. Roos-Mattjus· 1 shared S. Svartsjo· 1 shared V. Back· 1 shared V. Mezger· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

A. de Thonel

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1 paper

Recent·Most cited

Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2

L. Pesonen, S. Svartsjo, V. Back, A. de Thonel, V. Mezger, D. Saberan-Djoneidi, P. Roos-Mattjus

This study shows gambogic acid and gambogenic acid induce a thiol-dependent heat shock response by disrupting HSP90 interactions with HSF1 and HSF2, suggesting caution in their use as cancer therapeutics.

bioRxiv · Apr 26, 2021Cell Biology