Phage steering of antibiotic-resistance evolution in the bacterial pathogen Pseudomonas aeruginosa
J. Gurney, L. Pradier, J. S. Griffin, C. Gougat-Barbera, B. K. Chan, P. E. Turner, O. Kaltz, M. E. Hochberg
This study shows that phage OMKO1 can reduce antibiotic resistance in Pseudomonas aeruginosa both in vitro and in vivo, by selecting for antibiotic sensitivity and phage resistance.
bioRxiv · Dec 10, 2019Evolutionary Biology