Single nucleus sequencing fails to detect microglial activation
N. Thrupp, Carlo Sala Frigerio, L. Wolfs, Nathan Skene, S. Poovathingal, Y. Fourne, Paul McMahan Matthews, Tom Theys, Renzo Mancuso, Bart De Strooper, Mark W. E. J. Fiers
The paper shows that single nucleus RNA-Seq fails to detect microglial activation genes in human brain samples compared to single cell RNA-Seq.
bioRxiv · Apr 13, 2020 · PreprintNeuroscience