Chemerin Induced by Treponema pallidum Predicted Membrane Protein Tp0965 Mediates Endothelial Dysfunction via Activating MAPK Signaling Pathway
R.-L. Zhang, L.-J. Yang, Q.-Q. Wang
This study shows that Tp0965 induces chemerin in endothelial cells, which activates MAPK signaling and promotes endothelial dysfunction and monocyte migration, contributing to syphilis immunopathogenesis.
bioRxiv · Sep 20, 2018Microbiology