Author

Laurent Duret

Primary ORCID profile (0000-0003-2836-3463 · 8 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Laurent DuretiD8 papers · Lyon 1 Université

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Dmitri Petrov· 1 shared Florent Lassalle· 1 shared Nicolas Galtier· 1 shared Peter F Arndt· 1 shared Philipp W Messer· 1 shared Séverine Périan· 1 shared Sylvain Glemin· 1 shared Thomas Bataillon· 1 shared

Activity by Year

2014-2015 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperEvolutionary Biology

Dmitri Petrov

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2 papers

Recent·Most cited

GC-content evolution in bacterial genomes: the biased gene conversion hypothesis expands.

Florent Lassalle, Séverine Périan, Thomas Bataillon, Xavier Nesme, Laurent Duret, Vincent Daubin

This study shows that GC-Biased Gene Conversion (gBGC) is widespread in bacterial genomes, producing patterns similar to positive selection and affecting gene composition and base substitution patterns.

PLOS Genetics · Feb 6, 2015Peer-reviewedEvolutionary Biology

Quantification of GC-biased gene conversion in the human genome

Sylvain Glemin, Peter F Arndt, Philipp W Messer, Dmitri Petrov, Nicolas Galtier, Laurent Duret

This paper quantifies GC-biased gene conversion (gBGC) in the human genome using a new method that accounts for polarization errors and spatial heterogeneity, revealing that gBGC is concentrated in recombination hotspots.

bioRxiv · Oct 9, 2014Evolutionary Biology