Author

Leda Bencheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberto BoldriniiD· 1 shared Alessandro GalbiatiiD· 1 shared Alexandros PatsilinakosiD· 1 shared Andrea AstolfiiD· 1 shared C. RisueñoiD· 1 shared Carlo SantambrogioiD· 1 shared Carmine VarricchioiD· 1 shared Cassiano LanginiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alberto BoldriniORCID

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1 paper

Recent·Most cited

Protein Folding Interference Enables Selective Cyclin D1 Degradation

Alessandro Galbiati, Enrica Colasurdo, Alexandros Patsilinakos, Simone Lanfredini, Serena Bonifati, Tania Massignan, Carmine Varricchio, Leda Bencheva, Alberto Boldrini, Luca Terruzzi, Gianluca Papeo, Andrea Astolfi, Laura Raggi, Marta Pandini, Giulia Frapporti, , Giovanni Spagnolli

This paper identifies a folding intermediate of Cyclin D1 as a target for selective degradation, showing that pharmacological interference with this state inhibits tumor growth and overcomes resistance to CDK4/6 inhibitors.

bioRxiv · Oct 25, 2026 · PreprintBiochemistry