Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae
Trevor S. Cross, Facundo V. Torres, Nadia Nikulin, Abigail P. McGee, Leena Jalees, Rhea Balakrishnan, Tolani Aliyu, Lars F. Westblade, Abhyudai Singh, Tobias Dörr
This study identifies widespread meropenem tolerance in clinical Klebsiella pneumoniae isolates and reveals genetic mechanisms involving cell envelope stress responses and lytic transglycosylase MltB.
PLoS Pathogens · Jan 30, 2026Peer-reviewedMicrobiology