Stepped Cyclic Strain, that Increases or Decreases as Hierarchical Collagen Fibers Form, Does not Further Improve Maturation in Engineered Ligaments
Leia Troop, Jennifer L. Puetzer
This study tests stepped cyclic strain during collagen fiber formation in engineered ligaments and finds it does not improve maturation beyond existing methods.
bioRxiv · Aug 5, 2026 · PreprintBioengineering