Author

Letian Chen

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Gufeng YuiD· 2 shared Haoyang Luan· 2 shared Yang Yang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Gufeng YuORCID

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2 papers

Recent·Most cited

Centered cross-context perturbation transfer on the public 2025 Virtual Cell Challenge benchmark

Haoyang Luan, Letian Chen, Gufeng Yu, Yang Yang

The paper develops a method for cross-context perturbation transfer and differential-expression ranking, achieving competitive results on a benchmark challenge.

bioRxiv · Oct 25, 2026 · PreprintBioinformatics

An immune world model with multi-agent orchestration for peptide vaccines

Letian Chen, Haoyang Luan, Gufeng Yu

This paper develops an immune world model for peptide vaccines that links molecular predictions with immune dynamics through multi-agent orchestration and native-recognition constraints.

bioRxiv · Oct 21, 2026 · PreprintBioinformatics