A blastema in sea star larvae integrates wound signaling to drive regeneration-specific and developmental gene expression patterns.
Jon Lee Andrade, Andrew Wolff, Lexi Rios, Adel Fergatova, Veronica F. Hinman
The paper identifies a regeneration-induced blastema cell state in sea star larvae and shows how wound signals drive distinct gene regulatory networks for regeneration.
bioRxiv · Sep 22, 2026 · PreprintDevelopmental Biology