Single-cell spatial transcriptome reveals pathological features of human hippocampus with sclerosis
Lifang Wang, Xingjie Li, Yuyang Liu, Bufan Jin, Yanrong Wei, Youzhe He, Yaru Ma, Zi-Han Wu, Xue Gong, Yanru An, Xueying Kong, Yanan Xing, Ruixi Ye, Quyuan Tao, Aiqing Li, , Zhen Yi Hong
This study uses single-cell spatial transcriptomics to identify molecular and cellular changes in hippocampal sclerosis associated with MTLE, revealing vulnerable subregions and novel pathological features.
bioRxiv · Jan 21, 2025 · PreprintNeuroscience