Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteria
Yushu Chen, Lim J, Shu‐Sin Chng
This study investigates the role of trehalose in mycolic acid biosynthesis in mycobacteria, showing its essentiality through Pks13 specificity and demonstrating that trehalose dimycolate is dispensable for growth.
Proceedings of the National Academy of Sciences · Feb 17, 2026Peer-reviewedBiochemistry