Ophiuchus-Ab: A Versatile Generative Foundation Model for Advanced Antibody-Based Immunotherapy
Yiheng Zhu, Jian Ma, Mingze Yin, Jialu Wu, Lin Tang, Zhiyun Zhang, Qiuyi Li, Shikun Feng, Haiguang Liu, Tao Qin, Junchi Yan, Chang‐Yu Hsieh, Tingjun Hou
Ophiuchus-Ab is a generative foundation model for antibody design that captures inter-chain dependencies and predicts antibody properties like developability and binding affinity.
bioRxiv · Feb 4, 2026 · PreprintBioinformatics