Author

Lina Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ning WuiD· 3 shared Shuai NiiD· 3 shared Fengjiao Zhu· 2 shared Kejia KaniD· 2 shared Wei Wang· 2 shared Heng MeiiD· 1 shared Jinchang LuiD· 1 shared Jueyu WangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioinformatics

Ning WuORCID

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3 papers

Recent·Most cited

CESAR: A R Package for High-Sensitivity Detection of Copy Number Variations in ctDNA Using Segmentation and Anchor Recalibration

Jinchang Lu, Shuai Ni, Kui Lu, Ning Wu, Yun Wang, Lina Wang, X F Jiang

CESAR improves CNV detection in low-tumor fraction ctDNA by recalibrating depth ratios using anchor selection and segmentation, outperforming CNVkit in sensitivity and reproducibility.

bioRxiv · Jul 22, 2026 · PreprintBioinformatics

Systematic In Silico Off-Target Assessment of siRNAs: Integrated Tissue-Specific Scoring and Cross-Species Preclinical Model Selection with TargetSureR

Shuai Ni, Kejia Kan, Fengjiao Zhu, Lina Wang, Wei Wang, Ning Wu

TargetSureR assesses siRNA off-target risks using a seven-dimensional scoring system and enables cross-species model selection for preclinical safety evaluation.

bioRxiv · May 31, 2026 · PreprintBioinformatics

LISA: A Comprehensive R Package for Lentiviral Integration Site Analysis in Gene Therapy Safety Assessment

Shuai Ni, Ning Wu, Yun Jee Kang, Fengjiao Zhu, Jueyu Wang, Lina Wang, Wei Wang, Heng Mei, Kejia Kan

LISA is an R package for analyzing lentiviral integration sites in gene therapy to assess safety by identifying risk-associated genomic regions and tracking clonal dynamics.

bioRxiv · Dec 23, 2025 · PreprintBioinformatics