NeurosciencebioRxivPreprint
Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition
Noah R. Johnson, Athena C.-J. Wang, Christina M. Coughlan…·Huntington Potter
The paper identifies imipramine and olanzapine as inhibitors of apoE4-catalyzed Aβ polymerization, showing cognitive improvements in Alzheimer's patients.
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