Author

Esteban Lucero

University of Colorado Anschutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Heidi J. ChialiD· 3 shared Huntington PotteriD· 3 shared Noah R. JohnsoniD· 3 shared Breanna R. DoolingiD· 2 shared Christina M. CoughlaniD· 2 shared A. Ranjitha Dhanasekaran· 1 shared Anne Vielle· 1 shared Athena C.-J. Wang· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Heidi J. ChialORCID

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Author profile →

3 papers

Recent·Most cited

Trisomy 21 cerebral organoids exhibit Alzheimer's disease amyloid and apolipoprotein E co-pathologies

Breanna R. Dooling, Anne Vielle, Esteban Lucero, Catherine Rydland, Daphne Quang, Rose Summers, Hector Esquer, Christina M. Coughlan, Matthew D. Galbraith, Joaquin Maximiliano Espinosa, Daniel V. LaBarbera, Heidi J. Chial, Huntington Potter, Aurélie Ledreux, Noah R. Johnson

This study shows that trisomy 21 cerebral organoids exhibit Alzheimer's disease amyloid and apoE co-pathologies, with apoE playing a key role in the disease process.

bioRxiv · Jul 7, 2026 · PreprintNeuroscience

Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer's disease

Esteban Lucero, Ronald K. Freund, Noah R. Johnson, Breanna R. Dooling, Emily M. Sullivan, Olga Prikhodko, Md. Mahiuddin Ahmed, Mark L. Dell’Acqua, Heidi J. Chial, Huntington Potter

This study shows that overexpressing Kif11 rescues cognitive and synaptic deficits in Alzheimer's disease models.

bioRxiv · Sep 9, 2021 · PreprintNeuroscience

Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition

Noah R. Johnson, Athena C.-J. Wang, Christina M. Coughlan, Stefan Sillau, Esteban Lucero, Lisa Viltz, Neil E. Markham, Cody Allen, A. Ranjitha Dhanasekaran, Heidi J. Chial, Huntington Potter

The paper identifies imipramine and olanzapine as inhibitors of apoE4-catalyzed Aβ polymerization, showing cognitive improvements in Alzheimer's patients.

bioRxiv · Mar 28, 2021 · PreprintNeuroscience