An On-Demand Nanodisc Platform for Reconstitution of Functional Membrane Proteins into Model and Living Membranes
Long-Kai Chen, Yun-Shan Wang, Wei‐Hsuan Chang, Che-Kai Lin, Pei-Tzu Huang, Ming-Chang Yu, Wenxin Liu, Tzu-Ting Huang, Chien-Yu Ko, Ru-Hsuan Bai, Sheng‐Kai Wang, Yun-Wei Chiang, Chun‐Wei Lin
This paper develops a nanodisc platform for rapidly reconstituting functional membrane proteins into model and living membranes, demonstrating its effectiveness with calcium channels and GPCRs.
bioRxiv · Aug 19, 2026 · PreprintBiochemistry