Author

Lotta Andersson

Finnish Red Cross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Emmi JärveläiD· 3 shared Helka GöösiD· 3 shared Mira SaariiD· 3 shared Diana SchenkweiniD· 2 shared Erja KerkeläiD· 2 shared Farhana JahaniD· 2 shared Henrik PaavilaineniD· 2 shared Jan KoskiiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Emmi JärveläORCID

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3 papers

Recent·Most cited

Biomimetic virus-like mesoporous silica nanoparticles activate NK cells indirectly via monocyte crosstalk

Minna Sivonen, Silja Saarela, Jiajia Wang, Mira Saari, Emmi Järvelä, Lotta Andersson, Enkhzaya Batnasan, Leena Latonen, Helka Göös, Vesa‐Pekka Lehto, Wujun Xu

This study shows that biomimetic virus-like mesoporous silica nanoparticles activate NK cells through monocyte crosstalk by optimizing spike length, surface functionalization, and cell membrane coating.

Nano Letters · Aug 27, 2026Peer-reviewedImmunology

Efficient NK cell transduction with VSV-G-pseudotyped lentiviral vectors

Emmi Järvelä, Jan Koski, Farhana Jahan, Antti Tuhkala, Mira Saari, Manar Elmadani, Kari Salokas, Laurens Veltman, Lotta Andersson, Erja Kerkelä, Hekim Can, Marie C. Nyman, Seppo Ylä-Herttuala, Markku T Varjosalo, Diana Schenkwein, , Helka Göös

This study optimizes VSV-G-pseudotyped lentiviral transduction of NK cells by improving activation, construct design, and enhancer use, achieving high efficiency without compromising cell function.

Molecular Therapy Advances · May 5, 2026Peer-reviewedImmunology

Feeder cell - the key component in producing scalable and fit NK cells for therapeutic use

Mira Saari, Farhana Jahan, Lotta Andersson, Anna Syreeni, Pirjo Vehmaan-Kreula, Jan Koski, Emmi Järvelä, Erja Kerkelä, Henrik Paavilainen, Diana Schenkwein, Seppo Ylä-Herttuala, Kim K. Vettenranta, Helka Göös, Matti Korhonen

This study evaluates engineered K562 feeder cells for enhancing NK cell expansion and function in ex vivo cultures, showing up to 500-fold higher yields compared to feeder-free systems.

bioRxiv · Apr 23, 2026 · PreprintImmunology