Author

Lucie Madrange

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Frank YatesiD· 3 shared Jean‐Philippe Deslys· 2 shared Ágota ApátiiD· 1 shared Aloïse M MabondzoiD· 1 shared Anne-Cécile Guyot· 1 shared Antoine Aubert· 1 shared Aude Bramoulle· 1 shared Auriane MaïzaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Frank YatesORCID

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Author profile →

3 papers

Recent·Most cited

A robust and comprehensive quality control of cerebral cortical organoids: methodology and validation

Héloïse Castiglione, Lucie Madrange, Camille Baquerre, B. G. C. Maisonneuve, Thomas Lemonnier, Jean‐Philippe Deslys, Frank Yates, Thibault Honegger, Jessica Rontard, Pierre-Antoine Vigneron

This paper develops a standardized quality control framework for cerebral cortical organoids, validated through objective metrics and graded stress testing.

Scientific Reports · Aug 11, 2025Peer-reviewedNeuroscience

Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

Léa Broca-Brisson, Rania Harati, Clémence Disdier, Orsolya Mózner, Romane Gaston-Breton, Auriane Maïza, Narciso Costa, Anne-Cécile Guyot, Balázs Sarkadi, Ágota Apáti, Matthew R. Skelton, Lucie Madrange, Frank Yates, Jean Armengaud, Rifat Hamoudi, Aloïse M Mabondzo

This study uses human brain organoids to show that restoring SLC6A8 function in CTD patients normalizes protein expression and creatine uptake, suggesting potential therapeutic targets for CTD.

bioRxiv · Jun 1, 2023 · PreprintNeuroscience

A 3-dimensional molecular cartography of human cerebral organoids revealed by double-barcoded spatial transcriptomics

Gwendoline Lozachmeur, Aude Bramoulle, Antoine Aubert, François Stüder, Julien Moehlin, Lucie Madrange, Frank Yates, Jean‐Philippe Deslys, Marco Antonio Mendoza-Parra

This study develops a low-cost method for spatial transcriptomics and applies it to create a 3D molecular map of human brain organoids, showing gene expression differences across sections.

bioRxiv · Jan 18, 2023 · PreprintSystems Biology