Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements
V. Thormann, L. V. Glaser, M. C. Rothkegel, M. Borschiwer, M. Bothe, A. Fuchs, S. H. Meijsing
This study uses genome editing to add GR binding sites to genes, showing that a single site can make a gene a GR target, though results vary by gene.
bioRxiv · Dec 13, 2018Bioengineering