Cancer BiologybioRxiv
SLC7A11 is a superior determinant of APR-246 (Eprenetapopt) response than TP53 mutation status
K. M. Fujihara, M. Corrales-Benitez, C. S. Cabalag…·N. J. Clemons
This study identifies SLC7A11 expression as a better predictor of response to APR-246 than TP53 mutation status using cell line data and functional validation.
DOI 10.1158/1535-7163.mct-21-0067