Author

M. Direder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Copic· 4 shared H. J. Ankersmit· 4 shared K. Klas· 4 shared M. Mildner· 4 shared D. Bormann· 3 shared M. Laggner· 3 shared A. Mangold· 1 shared A. S. Ondracek· 1 shared

Activity by Year

2022-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCell Biology

D. Copic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The secretome of irradiated peripheral mononuclear cells attenuates hypertrophic skin scarring

V. Vorstandlechner, D. Copic, K. Klas, M. Direder, B. Golabi, C. Radtke, H. J. Ankersmit, M. Mildner

This study shows that secretomes from irradiated PBMCs reduce hypertrophic scarring in mice and humans by inhibiting fibrosis and promoting elastin expression.

bioRxiv · Dec 1, 2022 · PreprintCell Biology

Antithymocyte globulin inhibits CD8+ T cell effector functions via the paracrine induction of PDL-1 on monocytes

D. Copic, M. Direder, K. Klas, D. Bormann, M. Laggner, H. J. Ankersmit, M. Mildner

ATG increases PDL-1 on CD14+ monocytes and inhibits T cell effector functions.

bioRxiv · Jul 26, 2022Immunology

The effect of paracrine factors released by irradiated peripheral blood mononuclear cells on neutrophil extracellular trap formation

K. Klas, A. S. Ondracek, T. M. Hofbauer, A. Mangold, K. Pfisterer, M. Laggner, D. Copic, M. Direder, D. Bormann, H. J. Ankersmit, M. Mildner

This study shows that secretome from stressed PBMCs inhibits NET formation by reducing ROS, upregulating antioxidant proteins, and inhibiting PAD4 activation.

bioRxiv · May 30, 2022 · PreprintImmunology

Paracrine factors of stressed peripheral blood mononuclear cells activate pro-angiogenic and anti- proteolytic processes in whole blood cells and protect the endothelial barrier

D. Copic, M. Direder, K. Schossleitner, M. Laggner, K. Klas, D. Bormann, H. J. Ankersmit, M. Mildner

This study shows that paracrine factors from gamma-irradiated PBMCs alter gene expression in blood cells and protect endothelial barriers, suggesting potential therapeutic use in tissue repair.

bioRxiv · Apr 22, 2022 · PreprintCell Biology