A paradigm for post-embryonic Oct4 re-expression: E7-induced hydroxymethylation regulates Oct4 expression in cervical cancer.
T. Panayiotou, M. Eftychiou, E. Patera, V. Promponas, K. Strati
The paper identifies E7-induced hydroxymethylation as a mechanism regulating Oct4 re-expression in cervical cancer, affecting transcriptional patterns and cellular plasticity.
bioRxiv · Apr 10, 2023Cancer Biology