Author

M. GRAILLE

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:structural biology· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Chapat· 2 shared C. Moch· 2 shared I. Barbarin-Bocahu· 2 shared L. Zou· 2 shared A. Rigobert· 1 shared B. Garkhal· 1 shared B. PALANCADE· 1 shared C. Carapito· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

C. Chapat

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Author profile →

5 papers

Recent·Most cited

Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicase

I. Barbarin-Bocahu, N. Ulryck, A. Rigobert, N. Ruiz Gutierrez, L. Decourty, M. Raji, B. Garkhal, H. Le Hir, C. Saveanu, M. Graille

The paper identifies a conserved binding motif in Nmd4 that interacts with Upf1, showing its role in NMD and conservation in metazoan SMG6.

bioRxiv · Feb 27, 2024 · PreprintBiochemistry

The YTHDF1-3 proteins are bidirectionally influenced by the codon content of their mRNA targets

C. Moch, L. Zou, N. Pythoud, E. Fillon, G. Bourgeois, M. Graille, C. Carapito, C. Chapat

This study identifies that YTHDF1-3 proteins modulate mRNA translation and stability based on codon content, revealing bidirectional regulation of mRNA fate.

bioRxiv · Nov 20, 2023 · PreprintCell Biology

The SARS-CoV-2 protein NSP2 impairs the microRNA-induced silencing capacity of human cells

L. Zou, C. Moch, M. GRAILLE, C. Chapat

This study identifies NSP2 as a SARS-CoV-2 protein that disrupts microRNA-mediated gene silencing by interacting with the 4EHP-GIGYF2 complex.

bioRxiv · Jan 25, 2022 · PreprintCell Biology

Artificial intelligence to solve the X-ray crystallography phase problem: a case study report.

I. Barbarin-Bocahu, M. GRAILLE

This paper demonstrates using AlphaFold and RoseTTAFold to solve the crystal structure of a protein in the NMD pathway by overcoming limitations of molecular replacement.

bioRxiv · Dec 14, 2021 · PreprintBiochemistry

Formation of S. pombe Erh1 homodimer mediates gametogenic gene silencing and meiosis progression

D. HAZRA, V. ANDRIC, B. PALANCADE, M. ROUGEMAILLE, M. GRAILLE

This study reveals that Erh1 homodimer formation is essential for EMC complex function in meiotic gene silencing and progression in fission yeast.

bioRxiv · Sep 30, 2019Biochemistry