Author

M. Grulich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Palyzova· 2 shared B. Surpeta· 2 shared H. Maresova· 2 shared J. Brezovsky· 2 shared J. Zahradnik· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

A. Palyzova

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Author profile →

2 papers

Recent·Most cited

Engineering dynamic gates in binding pocket of penicillin G acylase to selectively degrade bacterial signaling molecules

M. Grulich, B. Surpeta, A. Palyzova, H. Maresova, J. Zahradnik, J. Brezovsky

This paper designs engineered variants of penicillin G acylase to selectively degrade bacterial signaling molecules, showing significant shifts in substrate specificity.

bioRxiv · May 9, 2023 · PreprintBiochemistry

Common Dynamic Determinants Govern Quorum Quenching Activity in N-terminal Serine Hydrolases

B. Surpeta, M. Grulich, A. Palyzova, H. Maresova, J. Brezovsky

This study identifies common dynamic determinants governing quorum quenching activity in N-terminal serine hydrolases through simulations and experimental validation.

bioRxiv · Jan 13, 2022Biochemistry