Author

M. Izutsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

R. E. Lenski· 2 shared A. Shibai· 1 shared C. Furusawa· 1 shared D. M. Lake· 1 shared H. Kotani· 1 shared J. P. Dodson· 1 shared Z. W. D. Matson· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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2 shared papersEvolutionary Biology

R. E. Lenski

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3 papers

Recent·Most cited

Non-monotonic Relationship between Mutation Rate and Speed of adaptation under Antibiotic Exposure in Escherichia coli

A. Shibai, M. Izutsu, H. Kotani, C. Furusawa

This study shows that higher mutation rates in E. coli do not always speed up antibiotic resistance evolution, revealing a non-monotonic relationship that varies by antibiotic type.

bioRxiv · Aug 15, 2023 · PreprintEvolutionary Biology

Experimental Test of the Contributions of Initial Variation and New Mutations to Adaptive Evolution in a Novel Environment

M. Izutsu, R. E. Lenski

This study compares the contributions of initial genetic variation and new mutations to adaptation in E. coli using different starting conditions in a new environment, finding that new mutations eventually contribute more to adaptation.

bioRxiv · May 31, 2022Evolutionary Biology

Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations

M. Izutsu, D. M. Lake, Z. W. D. Matson, J. P. Dodson, R. E. Lenski

This study investigates how periodic bottlenecks affect adaptive evolution in microbial populations, finding that the optimal dilution factor depends on the frequency of beneficial mutations.

bioRxiv · Dec 29, 2021Evolutionary Biology