Author

M. Laffranchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Del Prete· 1 shared A. Fra· 1 shared A. Mantovani· 1 shared C. Garlanda· 1 shared D. A. Lomas· 1 shared D. Bosisio· 1 shared E. L. K. Elliston· 1 shared F. Gangemi· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Del Prete

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Author profile →

2 papers

Recent·Most cited

SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8

V. Salvi, H. O. Nguyen, F. Sozio, T. Schioppa, M. Laffranchi, P. Scapini, M. Passari, I. Barbazza, L. Tiberio, N. Tamassia, C. Garlanda, A. Del Prete, M. Cassatella, A. Mantovani, S. Sozzani, D. Bosisio

This study identifies SARS-CoV-2 ssRNAs as activators of TLR7/8 and MyD88 pathway, leading to inflammation and immune responses in vitro and in vivo.

bioRxiv · Apr 15, 2021Immunology

Characterisation of a type II functionally-deficient variant of alpha-1-antitrypsin discovered in the general population

M. Laffranchi, E. L. K. Elliston, F. Gangemi, R. Berardelli, D. A. Lomas, J. A. Irving, A. Fra

The paper identifies and characterizes a novel alpha-1-antitrypsin variant, Gly349Arg, which is functionally deficient but not secretory impaired, highlighting the need for accurate genotyping in AATD patients.

bioRxiv · Oct 24, 2018Biochemistry