Cellular adhesion is a controlling factor in neutrophil extracellular trap formation induced by antineutrophil cytoplasmic antibodies
P. M. Lelliott, M. Nishide, N. Pavillon, Y. Okita, T. Shibahara, Y. Mizuno, H. Yoshimura, S. Obata, A. Kumanogoh, N. I. Smith
This study shows that neutrophil adhesion is essential for ANCA-induced NET formation and that targeting adhesion factors could prevent NET-mediated damage in AAV.
bioRxiv · Oct 19, 2021 · PreprintImmunology