Cell BiologybioRxiv
A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response
L. Milano, C. F. Charlier, R. Andreguetti…·L. B. Meira
This paper shows that alkyladenine DNA glycosylase (AAG) is required for alkylation-induced unfolded protein response (UPR) in mouse liver and human cancer cells, independent of its DNA repair activity.