Mechanistic Insights Into The Active Site And Allosteric Communication Pathways In Human Nonmuscle Myosin-2C
K. Chinthalapudi, S. M. Heissler, M. Preller, J. R. Sellers, D. J. Manstein
This study presents a crystal structure of human nonmuscle myosin-2C and identifies an allosteric communication pathway that affects nucleotide binding and release kinetics.
bioRxiv · May 17, 2017Biochemistry