Piggybacking on the Cholera Toxin: Identification of a Toxoid-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons
M. R. Balmforth, J. Haigh, C. Tiede, D. C. Tomlinson, J. Deuchars, M. E. Webb, W. B. Turnbull
The paper identifies two antibody mimetics that bind to cholera toxin B-subunit and demonstrate selective delivery to motor neurons in vivo.
bioRxiv · May 11, 2020Biochemistry