Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming
C. B. Brashears, R. Rathore, M. Schultze, W. R. Ehrhardt, S.-C. Tzeng, B. A. Van Tine, J. M. Held
The paper investigates the cellular response to arginine starvation in sarcoma cells using multi-omic profiling, revealing adaptive ERK signaling and Myc-Max transcriptional networks.
bioRxiv · Jan 13, 2020Cancer Biology