Conjugation of palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action
E. Leung, P. Tomek, M. Tercel, J. Reynisson, T. I. H. Park, E. Cooper, W. A. Denny, P. J. Choi, J. Jose
This study conjugates palbociclib with MHI-148, showing increased cytotoxicity in breast cancer cells but a different mechanism of action compared to palbociclib alone.
bioRxiv · Nov 2, 2021 · PreprintCancer Biology