Human XIST RNA acts early to condense architecture which facilitates A-repeat density-dependent initiation of gene silencing
M. Valledor, M. Byron, B. Dumas, D. M. Carone, L. L. Hall, J. B. Lawrence
This study shows XIST RNA condenses chromosome architecture early, which is necessary for gene silencing initiation, and that A-repeat density is critical for this process.
bioRxiv · Feb 4, 2022 · PreprintCell Biology