In vitro sexual dimorphism establishment in schistosomes
Rémi Pichon, Magda E. Lotkowska, Jude LD Bulathsinghalage, Madeleine McMath, Mary Evans, Benjamin J. Hulme, Kirsty Ambridge, Geetha Sankaranarayanan, Simon Kershenbaum, Sarah D. Davey, Josephine Forde-Thomas, Karl F. Hoffmann, Matthew Berriman, Gabriel Rinaldi
This paper refines an in vitro protocol for culturing schistosomes to achieve sexual dimorphism, showing that human serum promotes red blood cell digestion and sexual differentiation compared to fetal bovine serum.
eLife · Sep 10, 2026Peer-reviewedDevelopmental Biology