JAK2V617F Myeloproliferative Neoplasms Support Parallel Evolution of Independent Leukemic Clones
Tyler M. Parsons, Aishwarya Krishnan, Infencia Xavier Raj, Andrew L. Young, David R O’Leary, Jason Arand, Maggie Cox, Stephen T. Oh, Grant Anthony Challen
This study shows that leukemic clones can evolve independently of JAK2V617F in MPNs and contribute to disease progression through pro-inflammatory environments.
bioRxiv · Sep 23, 2025 · PreprintCancer Biology